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pentobarbital will lessen the level or impact of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.pentobarbital will reduce the level or influence of exemestane by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. For clients getting exemestane using a strong CYP3A4 inducer t